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Active Studies
Obsessive Compulsive Disorder Studies
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The purpose of this study is to investigate factors associated with symptoms of Obsessive-Compulsive Disorder (OCD) and Body Dysmorphic Disorder (BDD). This study will explore thinking patterns, behaviors, beliefs, and relationships in individuals and families with OCD and/or BDD and those without OCD or BDD. The goal of the study is to improve our understanding of factors that may contribute to the symptoms of OCD and BDD. Such knowledge may ultimately help us to develop prevention/early intervention strategies for these disorders. During participation, comprehensive assessments, including diagnostic interviews, computer tasks, and self-report measures will be administered to children diagnosed with OCD or BDD or no disorder as well to their first-degree relatives.
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This study is examining which areas of the brain are involved in attention (the ability to think, reason, and remember) in OCD. We are trying to understand whether people with OCD use certain areas of the brain differently than control participants or individuals with other disorders (schizophrenia, autism spectrum disorders) when performing tests of attention that involve eye movements. Different scans will be used to take pictures of your brain (Magnetic Resonance Imaging [MRI]) and brain function (special high-speed functional MRI [fMRI; MEG and EEG]) during certain tasks. This study will also look at your genes to find out if there are relationships between genes and brain function.
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This study is investigating how the brain is involved in emotional learning and memory in OCD.
Scans will be used to take pictures of participants' brains and brain function (using functional
MRI) while they undergo a procedure involving an annoying but not painful, half-second electric
current, applied to the fingers. This procedure will be conducted during two separate sessions in
an fMRI scanner.
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This study is for people with OCD who are not currently taking any other psychiatric medications (other meds, including birth control, are fine). The study runs for 17 weeks, and involves 6 visits to our clinic in Charlestown. During the first visit subjects are interviewed about their past psychiatric history, and complete a variety of questionnaires. The first study visit is the longest (1-2 hours), but visits after that take 20-30 minutes each. At these visits, subjects fill out some short symptom assessments, and discuss how treatment is going for them. At the final visit we will assess the patients' progress and discuss future treatment options. There is no compensation for the study, but the medication is provided free of charge. Patients who wish to enroll must not be on any psychiatric medications, nor can they be undergoing current behavior therapy. Patients with comorbid bipolar disorder or psychosis are excluded, as are patients who have had a depressive episode in the last 12 months.
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Body Dysmorphic Disorder Studies
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This is a medication treatment study for adults with Body Dysmorphic Disorder in collaboration with Butler Hospital that seeks to establish the efficacy of Escitalopram, also known as Lexapro, in the treatment of this disorder. Additionally, this study seeks to determine whether individuals who do well on Escitalopram will continue to do well after discontinuation of the medication. It is hoped that some of the gains made during medication treatment can be maintained after the treatment has ceased. Lexapro is among the most highly recommended medications for BDD, although there is currently no FDA approved medication for BDD. |
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This study is designed to gather
information about mental health symptom profile, treatment
barriers, and treatment utilization among individuals
suffering from Body Dysmorphic Disorder by Proxy (BDD-BP).
By examining the etiology, symptomatic profile, and
prevalence of this disorder, this study will collect
preliminary data that can be used to help further future
research to develop better treatment options for individuals
with BDD by proxy.
To participate, please use this link:
https://www.surveymonkey.com/s/BDDBYPROXY |
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The purpose of this study is to develop and test the effectiveness of Cognitive-Behavioral Therapy (CBT) for children and adolescents suffering from Body Dysmorphic Disorder. CBT is the most effective psychological treatment for adults with BDD. Information we have so far suggests that CBT might prove effective in treating children and adolescents with BDD as well.
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The purpose of this study is to investigate factors associated with symptoms of Obsessive-Compulsive Disorder (OCD) and Body Dysmorphic Disorder (BDD). This study will explore thinking patterns, behaviors, beliefs, and relationships in individuals and families with OCD and/or BDD and those without OCD or BDD. The goal of the study is to improve our understanding of factors that may contribute to the symptoms of OCD and BDD. Such knowledge may ultimately help us to develop prevention/early intervention strategies for these disorders. During participation, comprehensive assessments, including diagnostic interviews, computer tasks, and self-report measures will be administered to children diagnosed with OCD or BDD or no disorder as well to their first-degree relatives.
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In this research study we seek to investigate the
effectiveness of D-cycloserine as a memory booster for Exposure and
Response Prevention in the treatment of Body Dysmorphic Disorder.
D-cycloserine is an antibiotic that has been used in the treatment of
tuberculosis for over 20 years. Research so far demonstrates
D-cycloserine does increase the effectiveness of Exposure and Response
Prevention in the treatment of Obsessive Compulsive Disorder. We would
like to expand this research with D-cycloserine to see if it is effective
with body dysmorphic disorder. | |
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Tourette Syndrome & Tic Disorders Studies
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We are currently awaiting approval for a new treatment study for tics. Please check back soon!
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Other Studies |
We are no longer recruiting for the Olfactory Reference Syndrome study.
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